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SCALES — Load ZGF/COPE/HAMD/PANSS/SSCL16/SANS questionnaire data

Loads ZGF, COPE, HAMD, PANSS, SSCL16, and SANS questionnaire data from standard files as generated by the internet-based "Zurich Questionnaire Forms", available for all the above instruments. Subsequently, syndrome scores are computed and optionally stored in databank. Specifically, Master.VOX supports syndrome-oriented approaches to psychopatholog which replace the mere yes-no dichotomy of diagnostic classification schemes by dimensional quantities and represent a valuable extension of operational criteria. Patients are described in terms of multidimensional feature vectors, thus avoiding the considerable loss of information inherent in diagnostic schemes. Syndrome-oriented approaches are well suited to resolve, for example, the fine gradations of within-pair concordance of monozygotic twins concordant and discordant for schizophrenia, or the mutual differences of intra-family psychic abnormalities that must not reach diagnostic significance.

 
            Specificationlist:      SCALES
            ------------------------------
            I4 INST                      0  Default-value
            I4 PROT                      0  Default-value
            I4 SAVE                      0  Default-value
            I4 LGIN              Undefined
            R4 PMAX                20.0000  Default-value
 
            01 INST Selects instrument to be processed
            02 PROT Controls printer output
            03 SAVE Controls storage in databank
            04 LGIN Logical unit number of input-device
            05 PMAX Maximum percentage of missing data that is permissible
            06 DEMO Examples that illustrate program function
 
 
            - INST = 0: Zurich Health Questionnaire ZGF
                        Sets VOX-Scales 1-5: sex,age,education,height,weight
                   = 1: Coping Strategies Inventory COPE
                   = 2: Hamilton Depression Scale HAMD
                   = 3: Positive and Negative Syndrome Scale PANSS
                   = 4: SADS Syndrome Check List SSCL16
                   = 5: SADS Syndrome Check List Supplement SSCL-SUPPL
                   = 6: Scale for the Assessment of Negative Symptoms SANS
 
            - PROT = 0: No print output
                   = 1: Detailed protocol
                   = 2: Mean values and standard deviations
 
            - SAVE = 0: Data are to be analyzed but not stored in databank
                   = 1: Data are stored in databank (existing data kept)
                   = 2: Data are stored in databank (existing data replaced)
 
            - LGIN = q: Logical unit number of input-device (standard=6;
                        valid numbers are 46-96)
 
            - PMAX = p: Maximum percentage of missing data that is permissible
 
 
            - DEMO: Familial Syndrome Patterns in Psychiatry
 
           

Example

 
 
            &&START SCALES=Normative speech study zurich (study 600)
             INST=0,PROT=3,LGIN=72
 
 
           
voxFig11
Fig. 11: Striking similarity between mean quantitative syndrome patterns derived by averaging across index cases (n=136; green bars) and mean quantitative syndrome patterns derived by averaging across "affected" first-degree relatives (n=116; red bars), as revealed through multivariate cluster analysis of SSCL16 syndrome scores.
Please note: (1) there are considerable inter-individual differences in the quantitative syndrome patterns within the population of index cases and the population of "affected" first-degree relatives; (2) within-family comparisons of syndrome demonstrate that the familial aggregation of psychopathology syndromes does not occur in a homotypic way, i.e., family data do not provide evidence for genetic segregation.

Partners:
Everis, Spain
ETH, Switzerland
UZH, Switzerland
Freiburg, Germany
MA Systems, UK
Bristol, UK
Xiwrite, Italy
Ultrasis, UK
Jaume, Spain
Valencia, Spain
Lanzhou, China

 

EU-Grant (FP7):
248544

[ Comments and suggestions to Webmaster ] k454910@bli.uzh.ch
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